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Moreover, antibiotics can kill beneficial bacteria as well as harmful ones, leading to gut dysbiosis, and after stopping antibiotics, TMAO levels rise again

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10.2337/db11-1437 87 SavicaV.SantoroD.MazzagliaG.CiolinoF.MonardoP.CalvaniM.et al (2005)

For example, too much of the compound can cause headaches, which are particularly prominent The blood vessels in your brain become used to caffeines effects, so if you suddenly stop consuming this compound, it can cause a headache

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Second, characteristics of mitochondrial dysfunction in children with ASD and concomitant mitochondrial disease (MD) were compared with published literature of two general populations: ASD children without MD, and non-ASD children with MD