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doi: 10.1016/j.bmcl.2014.11.062

GSH-C4 Acts as Anti-inflammatory Drug in Different Models of Canonical and Cell Autonomous Inflammation Through NFkappaB Inhibition

The accumulation of iron in the brain may induce lipid peroxidation through oxidative stress, potentially triggering ferroptosis

328 In ALS, HSBP8 protects against aggregation of TDP-43 and its cleavage products (TDP-25 and TDP-35) by promoting their removal via autophagy, further illustrating the tight functional coupling between sHSPs and degradative pathways

Most recently, the ClearPoint system is being used with MRI-compatible materials for stereotactic localization with intraoperative imaging so that injection into the targeted structures can be visualized directly if the therapy is labeled with contrast agent

Both ALA and its reduced form DHLA act as potent antioxidants, capable of scavenging reactive oxygen species in various cellular compartments