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These symptoms can indirectly affect body weight because low energy often reduces appetite and activity

Li X, et al

These include regulation of mechanisms controlling reactive oxygen species (ROS), which cause macromolecular damage 16,17 , mitochondrial turnover or mitophagy 18 , and the mitochondrial unfolded protein response (UPR mt ), in which mitochondrial damage can be prevented by the removal of aggregated or unfolded proteins 19

DErcole AJ, Stiles AD, Underwood LE

Avoid touching the needle to the glass bottom of the vial, as this might dull its sharpness