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Moreover, cells expressing the mutant M8-03-G were hypersensitive to verapamil + L-BSO, similarly to wild-type MRP1 and mutant M8-03 cells (Fig

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The anti-STEAP2 monoclonal antibody (mAb) is conjugated via interchain cysteines to a maleimide-reactive, -glucuronidase -cleavable linker (HY-173635) bearing the topoisomerase 1 inhibitor, Exatecan (HY-13631)