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However, the effects of statins are not limited to decreasing lipid levels

Potential masking of underlying hepatic or systemic disease Delayed diagnosis due to symptom suppression Medical supervision is essential to ensure appropriate patient selection, correct dosing, and timely identification of adverse reactions

( a-j ) Comparison of the relative intensities of representative metabolites in neurons and the control samples in mice, including creatine ( a ), carnitine ( b ), l-proline ( c ), l-aspartate ( d ), glucosamine ( e ), l-histidine ( f ), l-3-phenylacetic acid ( g ), 2-hydroxyglutaric acid ( h ), putrescine ( i ), and glucosamine 6-phosphate ( j )

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This means that the antioxidant protection system of patients with allergic diseases is outdated compared to that of healthy individuals (Sackesen et al., 2008)

Endemic Balkan nephropathy, a progressive chronic nephritis in people living in areas bordering Danube River, is speculated to be caused by ochratoxins contaminated food as evidenced by the presence of ochratoxins in serum of families with endemic Balkan nephropathy and urinary tract tumors than in unaffected families [381-384]