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He discussed it explicitly in a 1983 paper he published with his graduate student Scott Appleton (2)

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As the last enzymatic step in the glycolytic pathway, a key part of lactate production involves efficient functioning of lactate dehydrogenase, especially LDHA, which is crucial in tumour growth and metastasis, such as lung cancer, liver cancer, breast cancer and PCs (235238)

DOI: Published online: September 6, 2023 1 Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea 2 Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Corresponding author: Tae Jung Oh Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam 13620, Korea E-mail: [email protected] Copyright 2023 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

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