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Defects in OCTN2 causes primary systemic carnitine deficiency presenting with cardiomyopathy and often myopathy and/or hepatic encephalopathy in early childhood, and is a treatable condition

It has been indicated that administration of MSG can induce activation of glutamate receptors which triggers the intracellular Ca 2+ signaling pathway

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In experimental diabetes the decrease in the eye of lens carnitine levels is an early important and selective event