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CRISPR was used to edit the immune-related genes of these cells so that the patients immune system would not attack them

Further research is needed to optimize the efficacy and safety of these therapeutic strategies and to translate preclinical findings into clinical applications for individuals with COPD (116)

Chemotherapy-related cardiomyopathy One of the major side effects of applying doxorubicin is potentially fatal cardiovascular toxicity, such as congestive HF and cardiomyopathy [145]

Front Physiol 2017

However, M2 macrophages are also implicated in promoting fibrosis, potentially via TGF- production or, a topic of ongoing discussion, direct transdifferentiation into myofibroblasts [10]