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Therapeutic doses are often in the range of 36 g/day Beneficial actions: 2030% reduction in total Reduces hepatic LDL cholesterol and triglycerides and VLDL synthesis Sharp increase in 2030% increase in circulating HDL2 fraction HDL-cholesterol 1015% reduction in mortality from coronary heart disease1 1

Furthermore, in contrast to GSH and Glu, the recently identified Riccas factor TGGs, was shown to rely on both GLR3.6 and GLR3.3 to trigger the systemic defense response 6

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However, metabolic imbalance is its Achilles heel

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Rapidly dividing human cells are the most sensitive to the damaging and killing effects of ionizing radiation (Novak et al., 1979