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In preclinical models, NNMT inhibition has been shown to mimic and boost exercise-mediated improvements in muscle function, even in sedentary subjects

Soares MO, Dumville JC, Ades AE, Welton NJ (2014) Treatment comparisons for decision making: facing the problems of sparse and few data

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You could also have blood tests done to determine your current B12 levels

Research in rats showed increased brain levels of dopamine, the nerve chemical that declines as Parkinsons symptoms worsen, after thiamine administration 10