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Headaches One of the most common symptoms of B12 deficiency is headaches

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Some evidence suggests a link between low vitamin B12 levels to a higher risk of dementia, Alzheimers disease, and Parkinsons disease

"Maternal vitamin B12 status and risk of neural tube defects in a population with high neural tube defect prevalence and no folic Acid fortification"

After initiation and dose increases, patients should be observed carefully for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back and which may or may not be accompanied by vomiting)

Unless an athlete has an approved Therapeutic Use Exemption (TUE), the use of substances when they are prohibited in sport may lead to an anti-doping rule violation and sanction