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dNP2 is a bloodbrain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis

We conducted burden testing in European males and females for effects on inverse normally transformed UKBB MRI Proton Density Fat Fraction (PDFF) (N=30,050 males and 32,135 females) and UKBB ICD-based NAFLD (N=172,664 males and 208,795 females) with Regenie

These insights dovetail with human fMRI studies showing attenuated ventral striatal activation during reward tasks in depressed alcoholics

Interestingly ACSL4 was preferentially expressed in a panel of basal-like breast cancer cell lines and predicted their sensitivity to ferroptosis (68)

Plant Cell Environ 23(8):853862

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