neuronal glutathione synthesis in vivo Metabolism of the Brain—The Role of Astrocytes The glutathione cycle shapes synaptic

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In fact, the S1 subunit alone was observed to induce an increased production of IL-6 and activation of NF-B and in consequence, inflammation in endothelial cells (334), and circulating S1 induced the expression of TLR2, TLR4, NLRP3, IL-1, TNF and HMGB1 in rats at 24 h after treatment, and TLR2, TLR4, NLRP3 and IL-1 remained overexpressed even after seven days (335)

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