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141,142 Recurrent somatic mutation of residues are mainly located at enzymatic active sites that bind to isocitrate, typically at R132 including R132H, R132L, R132S, R132C, and R132G in IDH1, and R140Q or R172K in IDH2

Furthermore, enzymatic depletion of polyP from cells achieved by overexpression of the mitochondria-targeted yeast polyphosphatase (MTS-GFP-scPPX1) significantly impaired respiratory chain activity (Abramov et al., 2010)

The formulation exhibited a %T value of 98.21 2.31%, indicating high clarity and transparency, characteristic of a well-formed nanoemulsion

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Serle said, noting that episcleral venous pressure is the most distal resistance to trabecular outflow