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A recent review has documented this synergy (McGuire et al., Curr Rev Musculoskelet Med 2025)

Tucson: City of Tucson, 1926

The study showed that the administration of 10.000 ugr of hydroxocobalamin nasal drops twice weekly was associated with a significant increase in vitamin B12 serum levels over the course of 3 months, starting from a median of 328 pmol/l (range 244429) to 973 pmol/l (range 4731,476)

Regular doses of Vitamin B12 are recommended to see the best results as our bodies do not store this vitamin for very long

One is a class action lawsuit from patients who experienced thrombosis after receiving the shot, and another is from a woman who was a clinical trial participant in the US