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Conversely, efficient metabolic transitions can benefit health and influence lifespan, as evidenced by reduced disease incidence and prolonged lifespan associated with fasting 2,3,4,5,6

Dirkx MF, Zach H, Van Nuland A et al (2019) Cerebral differences between dopamine-resistant and dopamine-responsive Parkinsons tremor

6.6.5 Thyroid hormones Thyroid hormones are associated with the oxidative and antioxidative status of an organism because of their role in regulating oxidative metabolism and in the formation of ROS (281)

Epigenetic reprogramming involves multiple layers, including DNA methylation, histone modifications, and chromatin remodeling, which can regulate gene expression patterns, leading to functional transformations in T cells during their long-term adaptation to the TME (60)

Schwer, B

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