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Metabotropic glutamate receptors Glutamate activates mGluRs after synaptic release, which are widely expressed in the peripheral and central nervous systems (CNS) and play multiple neuroregulatory roles [25,26,27,28]

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While these results support the potential of this platform for targeted antioxidant therapy, further investigations are required to optimize its formulation, evaluate long-term safety, and assess translational feasibility