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In this model, cytokines are not detected until 4 h of a single intravenous (i.v.) injection of CpG-ODN, a peak of cytokines is detected 6 h after the insult and cytokines levels rapidly decreased to basal levels at 12 h (ref

de Jong, W.W., Mulders, J.W., Voorter, C.E., Berbers, G.A., Hoekman, W.A., Bloemendal, H.: Post-translational modifications of eye lens crystallins: crosslinking, phosphorylation and deamidation

doi: 10.3390/ijms21207452 26 PeronRVatanabeIPManzinePRCaminsACominettiMR

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The study suggests that testosterone amplifies the islet impact of the hormone, which is currently used as a diabetes treatment

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