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however, overall histone acetylation was not enhanced by chronic ethanol treatment

Inhibition of GRP78 expression using siRNA abrogated TNF- or TGF--induced proliferation of FLS and up-regulation of cell cycle protein D1, thereby promoting cell death

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In the nucleus of M1 macrophages, key transcription factors such as NF-B, signal transducer and activator of transcription 1 (STAT1), STAT5, and interferon regulatory factor 3 (IRF3) regulate the gene expression of M1 macrophages, while M2 macrophages are regulated by transcription factors such as STAT6, IRF4, peroxisome proliferators-activated receptors (PPAR) and PPAR [93]

Couturier, J., Jacquot, J

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