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Reliable studies require strict control of the active peptide as variations in formulation can affect the outcome

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Thus, tropical areas that get more year-round sun and more direct sun (almost 90 degrees, straight down for most of the year at noon) have warmer surface waters than polar areas that may have no sun at all for several months each year and then very steep angles of the sun's rays (never directly overhead at noon)

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Animal studies document dramatic improvements in wound closure, granular tissue formation, and blood vessel growth at injury sites