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FIGURE 3 3.3 GHK-Cu promoted mucosal healing GHK-Cu treatment significantly enhanced of ZO-1 and Occludin expression in colitic mice, which were downregulated by DSS (Figures 4AC)

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Of approximately 4,000 affected genes, 59% are upregulated while 41% are downregulated, generally shifting expression patterns from diseased toward healthier states

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Journal of Medicinal Chemistry, 57 (22), 9220-9231