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Ann Gen Psychiatry

Gut-Skin Axis: Current Knowledge of the Interrelationship between Microbial Dysbiosis and Skin Conditions

Within the cell, iron storage proteins, transporters, and other factors are regulated to ensure adequate but nontoxic iron levels in cellular, as well as enough storage in the event of iron over capacity

Furthermore, a glutamate/GABA imbalance has also been found to be associated with anxiety disorders, which provides further support that anxiety disorders may, in part, be caused by a disruption in the excitatory-inhibitory balance (111)

Nevertheless, relative glutamatergic excess appears to be specific to early stages of illness [8], and relates to more severe symptoms at presentation [17], as well as gray matter decline [19], cognitive [20], and functional [16, 17] impairments

J Chin Med Assoc