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How Vitamin B12 May Affect Your Skin The proposed mechanism by which vitamin B12 influences acne development involves the skin microbiome, particularly the bacterium Cutibacterium acnes (formerly Propionibacterium acnes ), which naturally resides in hair follicles and sebaceous glands

R.MacdonaldR.et al

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Cells were cultured in RPMI-1640 medium (#PM150110, Procell, Wuhan, China) supplemented with 10% FBS (#A5670701, Gibco, USA) and 1% penicillin/streptomycin (#G4003, Servicebio, Wuhan, China) and were propagated with 5% CO 2 at 37 C