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It is also not always evident in the course of a chronic wound history when there is a need to reduce or stimulate ROS production, hence the importance of allying possible treatment strategies that target ROS with the use of sensors that could translate the actual needs of the wound at that given moment 193

doi: 10.1093/gerona/glac135

PERK, Protein kinase R-like Endoplasmic Reticulum Kinase

JS, AH, SW, and JG: review and editing

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