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But injections of hyaluronic acid might also be indicated in individuals with: Intolerance or contraindications to nonsteroidal anti-inflammatory drugs (NSAIDS) Patients who are poor surgical candidates Chondrocalcinosis Any type of cartilage injury Clinical evidence shows support for using intra-articular hyaluronic acid in individuals intolerant to NSAIDS and those wishing to defer or not willing to undergo surgery

Initially, injections may be given weekly or biweekly until levels improve, followed by maintenance doses every 1-3 months

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Serum proteins were labeled with iTRAQ tags, with each group of samples labeled separately

Sleep 27 : 12551273

145 In contrast, Zhou et al