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GSH depletion could lead to the overproduction of reactive oxygen species which can disrupt mitochondrial transmembrane potential and lead to mitochondrial dysfunction [32]

The TCA product -ketoglutarate can be converted to glutamate, which is converted to glutamine by glutamine synthetase, an enzyme that is predominately, if not exclusively, located in astrocytes [20]

Adequate nutrition is crucial for maintaining the health of the mother throughout pregnancy and for the growth and development of the fetus

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During your appointment, Dr Berkowitz will also be able to offer an estimation of what results you can expect and the possible duration of your Skin Brightening programme

doi: 10.1038/nature14156 74 YuCHDavidsonSHarapasCRHiltonJBMlodzianoskiMJLaohamonthonkulPet al