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ADO leads to tumor growth and skews the immune cells toward an immunosuppressive phenotype ( Figure 2 Adenosinergic pathways identified on different cell populations ( ADO is produced from the catabolism of mono- and di-nucleotides of adenine (ATP, NAD + and cAMP) (Figure 1)

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Species Several ASVs mapped with high confidence directly to a specific species (Supplementary Table S4), with considerably more species mapped using the BLASTn method compared to the BLCA method