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This combination of actions is associated with meaningful reductions in body weight, primarily through appetite suppression and slowing of gastric emptying

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Nature 342, 440443

5.3 Exercise regulates exerkines expression Exerkines are bioactive molecules secreted by exercise-stimulated tissues such as skeletal muscle, adipose tissue, liver, brain, and other organs, including myokines, cardiokines, hepatokines, adipokines, neurokines, lactate, and miRNAs