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This may be caused by an inflammatory response in the tissue surrounding the spleen's blood vessels, which can exert pressure on the blood vessels and lead to splenic infarction [116]

Neurosurgery (2013) 72(1):3341

These single-cell expression profiles systematically delineate the spatiotemporal regulation patterns of ferroptosis-suppressing signature genes within the renal disease microenvironment, providing direct cellular and molecular evidence for elucidating the mechanisms of ferroptosis imbalance in AKD and CKD pathogenesis, while offering important references for subsequent research on intervention strategies targeting ferroptosis-suppressing pathways in kidney diseases

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EAAT2 is responsible for greater than 90% of glutamate transport into crude synaptosomes 14 and is the predominant glutamate transporter in the brain, except for some regions, including the cerebellum, circumventricular organs and retina, where EAAT1 is the major transporter