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B ring of flavonoids is very important in scavenging radicals, most frequently via hydrogen-atom and/or electron transfer to hydroxyl, peroxyl, and other radical species

10.1074/jbc.271.19.11039 55

It is also the bodys main filter

Polycyclic aromatic hydrocarbons (PAHs), nitro-PAHs and related environmental compounds: biological markers of exposure and effects

Proteins belonging to the B-cell lymphoma 2 (BCL-2) family, which regulate the mitochondrial apoptotic pathway, represent a promising target in this context 7

Here's a breakdown of the big issues and power players you need to know to wrap your head around the fiery debate