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In mammals, tyrosinase organizes the melanin synthesis to defend the skin from harmful effects of ultraviolet (UV) radiations 17 , while hyperpigmentation disorders noted to promote freckles, melisma, pigmentation, petaloid actinic tanning, solar lentigo, and senile lentigines malignant melanoma 18,19,20

They undergo a dynamic process of fusion and fragmentation, known as mitochondrial dynamics, to maintain internal structure stability, eliminate damaged mitochondria, and meet cellular metabolic demands

Paraoxonase-1 and Oxidative Status in Common Mediterranean beta-Thalassaemia Mutations Trait, and Their Relations to Atherosclerosis

39 parallel (17, 23, 4368, 7080) and 2 cross-over (16, 69) studies were included in this study

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