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elegans fail to cross efficiently from the lumen of the intestine into the tissues

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Firstly, GA significantly upregulates key drug-metabolizing enzyme genes (e.g., Cyp2b13 , Cyp2c69 , Cyp3a44 , Cyp3a16 , and Fmo3 ) that are downregulated by TGT, thereby enhancing liver detoxification capacity (Shi et al., 2021)

They are being investigated for a wide range of diseases, including cancer [4], metabolic disorders [5], autoimmune conditions [6], and wound healing [7, 8]