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The sustained levels may also increase the likelihood of certain side effects, particularly joint stiffness and water retention

To read more on this, see our article: Vitamin B Complex

However, B-12 shots may have other side effects

Orthopaedic journal of sports medicine, 6(10), 2325967118804544

Liposomal formulations may improve penetration and stability

Gastrointestinal conditions such as celiac disease, Crohns disease or surgical changes like gastric bypass Older adults who may have reduced B12 absorption People who follow a strict vegetarian or vegan diet, as B12 is mainly found in animal-based foods People taking medications like PPIs or metformin or those with folate deficiency Real reddit experiences Below are some first-hand accounts from Reddit users: I was diagnosed with pernicious anemia after months of fatigue and neuropathy