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Furthermore, emodin demonstrated suppressive effects on LPS-triggered TLR2 and NF-B expression within NRK-52E cells

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Hearts showed a high propensity for arrhythmias at the onset of reperfusion (Figure 6A), and hearts that were perfused with 4-ClDzp before ischemia showed significantly lower incidence of arrhythmias (Figure 6B)

[DOI] [PMC free article] [PubMed] [Google Scholar] 186.Chang C.H., Tsai W.C., Lin M.S., Hsu Y.H., Pang J.H

Consequently, it was hypothesized that GSTs might reduce the reactive cyclopentenone ring to an unreactive ring