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Oxidative transformations can lead to the production of related metabolites and derivatives, such as Aflatoxin M1 (AFM1) and Aflatoxin Q1 (AFQ1), found as metabolites in animal tissues or derived from environmental modifications (De Oliveira et al

doi: 10.1016/j.immuni.2013.02.003 41

2023), stopping the GPx enzymatic reaction as the primary substrate, as shown in Scheme 1

Studies have shown that trypsin induces the release of calcium ions from vascular endothelial cells, causing coronary artery-dependent vasodilation and reducing the contractile sensitivity of smooth muscle [79]

doi: 10.1113/ep092191 Low-volume combined aerobic and resistance high-intensity interval training in type 2 diabetes: a randomised controlled trial

A line of recent reviews also revisited pharmacological potentials of black cumin in the prevention of COVID-19 and the associated complications [274,275,276,277]