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Low levels of vitamin B12 can lead to fatigue and anemia in milder cases

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Mass Spectrometry Identity Confirmation LC-MS is run on every lot to confirm the molecular ion matches the theoretical 1815.1 g/mol value for CHNOS

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2 Grip Strength and Exercise Endurance in Aged Mice Dimet-Wiley et al., Scientific Reports (2024) This study compared 5-Amino-1MQ treatment, voluntary wheel-running exercise (PoWeR), and combined treatment in aged C57BL/6J mice

The investigators interpreted the effects as direct pharmacological validation of the NNMT-knockdown phenotype reported earlier in genetic models