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Mark Thurston, who took over as Anglian's chief executive in July last year from Peter Simpson, said: "It will take time and investment to achieve a significant reduction in spills, but we are making good progress." He said the company has allocated 1bn to fund measures aimed at halving the number of spills by 2030

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Some symptoms of hangovers include weakness, nausea and vomiting, headaches, dizziness and shakiness, increased heart rate, and impacted sleep and concentration

475,476 Chronic hyperglycemia-induced neuronal damage to the autonomic fibers innervating the bladder and genitalia leads to impaired neurotransmission

This deficiency can result from conditions such as pernicious anemia, certain gastrointestinal disorders, or a diet low in animal products

Hardingham GE, Arnold FJ, Bading H (2001) A calcium microdomain near NMDA receptors: on switch for ERK-dependent synapse-to-nucleus communication