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They may recover fully within three months

The expression of CYP2E1 and CYP1A2, which played key roles in the conversion of APAP to NAPQI [34, 35], showed no significant difference between APAP and APAP_BSL group (Supplementary Fig

However, there are multiple pathways that result in upregulation of COX-2 in brain neurons, including increased N-methyl-D-Aspartate (NMDA) receptor-dependent activity (230), cerebral ischemia, seizures, and diseases such as AD or PD (231)