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These components are identified as the primary phytochemicals responsible for the pharmacological effects, including antioxidative, anti-inflammatory, antifatigue, and anticancer activity [98, 137]

As a typical amphiphilic structure, LNPs can simultaneously load both hydrophilic and hydrophobic drugs, thereby mimicking natural cell membranes and significantly enhancing cellular uptake and endocytosis processes (45)

A deeper understanding of these interconnected pathophysiologic mechanisms will facilitate the development of targeted therapies beyond cysteamine, optimizing treatment approaches to mitigate disease progression [146]

Dean, A

Gut microbiota in obesity and metabolic abnormalities: A matter of composition or functionality