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Finally, a meta-analysis confirmed this counterproductive effect, showing a reduced efficacy in patients undergoing combination therapy

Additionally, the interaction between follicular helper T cells and B cells plays a crucial role in the formation of tertiary lymphoid structures, which promote local antibody responses at sites of chronic inflammation [52]

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Schulman JD, Goodman SI, Mace JW, Patrick AD, Tietze F, Butler EJ: Glutathionuria: inborn error of metabolism due to tissue deficiency of gamma-glutamyl transpeptidase

[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Rasheed M.Z., Tabassum H., Parvez S