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DECLARATIONS Authors contributions Developed the model, ran simulations and analyses, interpreted the findings, and contributed to the writing and editing of the manuscript: Cruikshank A, Reed MC, Nijhout HF Availability of data and materials Computer models and codes used in this paper can be obtained from the authors by request

Gene expression remodeling: Research by Pickart and Margolina identified over 4,000 human genes regulated by GHK-Cu, including many involved in tissue repair and immune modulation