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The beta cells in type 2 diabetes are also adversely affected by chronic hyperglycemia, with this relentless deterioration in cell function, due to constant exposure to supraphysiologic concentrations of glucose, is termed glucose toxicity

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Int J Mol Med 47(5):19 Shino H, Hasuike A, Arai Y, Honda M, Isokawa K, Sato S (2016) Melatonin enhances vertical bone augmentation in rat calvaria secluded spaces

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doi: 10.3389/fmicb.2020.562048 53 WuJMOraeeADoonanBBPintoJTHsiehTC

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Hepatoprotective and symptomatic supportive treatments were administered for clinical management of severe liver injury, including the following (note: these treatments are used for clinical supportive care at our institution, and evidence from large-scale clinical trials for their efficacy in severe liver failure is limited): Monoammonium glycyrrhizinate cysteine sodium chloride injection 200 mL, qd, intravenous drip [ivgtt] for 4 consecutive days

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