t acetyl-l-carnitine L-Carnitine and roles and neuroprotection in developing brain Acetylcarnitine - Wikipedia

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To further refine the GSS-based strategy, we thus asked if a reference constructed solely from top-ranked hypomethylated DMCs could outperform a reference combining both hyper- and hypomethylated DMCs, and a reference constructed using only top-ranked hypermethylated DMCs

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While robust clinical trial data specific to these combinations continues to emerge, the physiological rationale and supporting evidence from component studies provide a sound basis for clinical application in appropriately selected patients

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Biophys Acta 2008, 1781, 97)