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To survive heat stress, plants deploy various adaptive mechanisms, such as maintaining cell membrane integrity, scavenging ROS, synthesizing antioxidants, accumulating osmoprotectants for osmoregulation, and activating kinases, including calcium-dependent protein kinases (Kumar et al., 2024a)

J Biol Chem 277:3621636222

12 BaryginaV.BecattiM.LottiT.MorettiS.TaddeiN.FiorilloC

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Among them, 176 had Liver Frailty Index (LFI) assessments about one year from the initial evaluation and were categorized as non-frail, pre-frail, or frail, and as sarcopenic or non-sarcopenic based on MRI

Patients frequently report this as the first noticeable improvement