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Gadow KD, Roohi J, DeVincent CJ, Kirsch S, Hatchwell E

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Emerging therapies targeting ferroptosisincluding inhaled nanoparticles delivering GPX4 mRNA or siRNA against ER/ACSL4show promise in preclinical models by selectively inhibiting lipid peroxidation without systemic immunosuppression ( 5 Immune cells and ferroptosis in asthma Immune cells are central contributors to the pathogenesis of asthma, but their roles extend beyond simple pro- versus anti-ferroptotic categorization

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Increases glucose uptake and the expression of PPARG in insulin-resistant adipocytes

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FIGURE 3 6.1.2 COX-2-PGE 2 -EP4 axis in RCC In most cell types, activated EP4 receptors are regulated by lipids and intracellular messengers such as cAMP (Fong et al., 2021) (Figure 3)

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& Roden, M

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Metabolic reprogramming and interventions in endometrial carcinoma

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