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DNA testing required for formal diagnosis (not a first-line investigation, exclude other causes first) Pre-pregnancy carrier testing of partner is important Rare causes of microcytic anaemia Chronic inflammation Lead poisoning (high blood lead level) Sideroblastic anaemia Normocytic normochromic anaemia Haemolytic anaemia Acute haemolysis in childhood can be a life-threatening illness and all cases should be discussed with a haematologist Admit children with haemolytic anaemia for observation

The ideal candidate is a patient who has hit a hard plateau on a GLP-1 receptor agonist and complains of significant fatigue or lethargy

If lifestyle changes and common supplements havent helped, it may be time to explore whats happening on a deeper, cellular level

Niacinamide helps improve skin texture and reduce pigmentation