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Though MPT was initially studied only in the context of pathophysiology, it is now being recognized that it could also have physiological roles [99], such as in the heart [100] and in calcium buffering in neuronal cells [101]
[DOI] [PMC free article] [PubMed] [Google Scholar] Balchandani P., Naidich T.P
125 SparrowJ
Liang H, Yoo S-E, Na R, Walter CA, Richardson A, Ran Q
However, the complex nature of pathophysiological mechanisms underlying mitochondrial metabolism in MS poses challenges for disease diagnosis and treatment