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Neoadjuvant chemotherapy is associated with increased expression of DNA repair proteins and epithelial to mesenchymal transition (EMT) in patients with non-small cell lung cancer (NSCLC)

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Variable protein expression in platelets found evidence that the delE155 enzyme is present in platelets obtained from subjects that are heterozygous for the GSTO1delE155, K208 allele E173K site-directed mutagenesis of isozyme GST T1-1, the mutant shows reduced expression levels and enzyme activity with all substrates compared to the wild-type enzyme

One of the most famous of these enzymes is cathecol-O-methyltransferase (COMT), which is known for its role in metabolizing estrogens and catecholamines