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TSS pathway activity is suppressed by excess hemin under hypoxia, and the suppression is reversible through DMF treatment The afore findings suggest that supplementing cystine at physiological concentrations is a prerequisite for investigating the function of CBS in SCD erythroblasts

The endothelium, the inner lining of blood vessels, plays a vital role in maintaining vascular homeostasis by regulating vasodilation, blood flow, and platelet aggregation [65]

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Third, cancer cells maintain robust antioxidant defenses

Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria

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