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A newer gene therapy that holds promise for the treatment of hearing loss is CRISPR/Cas9-based genome-editing, in which segments of DNA are added, removed, or altered

10.1016/S2468-1253(19)30342-5 116 SatyanK

4.6.4 Neuroinflammation Central and systemic inflammation play a role in ALS pathogenesis, with some immune cell targets [8, 233] leading to investigational considerations (Table 4)